Tuesday, 24 February 2015

Pathogens mentioned in different pharmacopoeias with ATCC number and morphological characters.

In pharmaceuticals, pathogen testing is very important and critical testing in which different media are used to identify whether specified pathogen is present in the product or not. This pathogen identification is part of Microbial limit testing (MLT) in which first enrichment of sample is performed and then enriched sample is streaked on different media to identify the pathogens. Pathogens should be absent from the sample as per pharmacopoeia. If pathogen is present in the sample then product is not suitable for use. Different pharmacopoeias ask for testing of different pathogens. Below is the table showing list of pathogens as per IP,BP and USP.
ATCC number and morphological characteristics are also mentioned in this table.

S.No.
Name of Pathogens to be tested as per different Pharmacopoeia
ATCC No.
Morphological characters
IP
BP
USP
1
Bile tolerant gram negative bacteria
Bile tolerant gram negative bacteria
Bile tolerant gram negative bacteria
NA
Gram negative rod shaped
2
Escherichia coli
Escherichia coli
Escherichia coli
8739
Gram negative rod shaped
3
Salmonella
Salmonella
Salmonella
14028
Gram negative rod shaped
4
Staphylococcus aureus
Staphylococcus aureus
Staphylococcus aureus
6538
Gram positive round shaped
5
Pseudomonas aeruginosa
Pseudomonas aeruginosa
Pseudomonas aeruginosa
9027
Gram negative rod shaped
6
Clostridia
Clostridia
Clostridia
19404
Gram positive drum stick shaped
7
Candida albicans
Candida albicans
Candida albicans
10231
Gram negative rod shaped
8
Shigella
Not mentioned
Not mentioned
12022
Unicellular yeast

Thanks!

3 comments:

  1. is Candida albicans Gram "negative rod shaped"?

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  2. candida albicans is it bacteria? i think so it is yeast. so there is no question of gram positive or gram negative..give confirmation.

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